Analogues de nucleoside cyclique 3', 5' pour le traitement du virus de l'hepatite c (vhc)

3', 5' - cyclic nucleoside analogues for treatment of hcv

Abstract

La présente invention concerne des composés représentés par la formule (I), dans cette formule, B représente un groupe hétéroaryle contenant de l'azote monocyclique à 6 ramifications ou un groupe hétéroaryle contenant de l'azote bicyclique 5 + 6 fusionné, et A est choisi dans les groupes (1), (2), (3) et (4), lesquels groupes sont tels que définis dans la description. Les composés décrits dans cette invention sont utiles pour le traitement d'une infection par le virus de l'hépatite C.
This invention provides compounds according to formula (I) where B is a 6-membered monocyclic nitrogen-containing heteroaryl group or a 5 + 6 fused bicyclic nitrogen-containing heteroaryl group, and A is selected from Groups (1), (2), (3), and (4) where Groups (1), (2), (3), and (4), are defined herein. These compounds are useful in the treatment of Hepatitis C infection.

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